Matt, Chris, and Jen talk about a study of whether low-dose aspirin to prevent vascular events should be weight dependent, the gang revisits placebo effects, and Jen focuses on the empathy of our dogs.
Matt, Chris, and Jennifer Rider (our first ever guest host) discuss a pragmatic trial of smoking cessation, examine the pros and cons of surrogate endpoints, and Chris schools us all on horse dentistry.
Matt, Chris, and Don review the literature on whether labelling can reduce food purchase and consumption, the gang discusses a series of trials that were found to have errors, and Chris calculates the sum total of all living things on earth.
Matt, Chris, and Don examine a study that looked at whether a vaccine can treat Type 1 diabetes, the gang discusses the “Loss of Confidence Project," and Matt reports on an N of 1 study that suggests red wine may be good for blood sugar.
Matt, Chris, and Don do their second ever live podcast, exploring a study on the effects of sleep on mortality, the gang discusses a proposal to change the definition of statistical significance, and Chris goes rogue and has three amazing and amusing articles.
Matt, Chris, and Don examine a trial using synbiotics to prevent neonatal sepsis, the gang discusses scientific productivity over time, and Don gives us just a study title for his amazing and amusing.
Matt, Chris, and Don discuss a new treatment for lung cancer (immunotherapy), the gang discusses a large clinical trial that controversially changed its endpoint, and Chris dives into the world of linguistics (again).
Matt, Chris, and Don look at a drug company antidepressant trial in adolescents that was re-analyzed by different authors who came to different conclusions, the gang discusses the pre-registration movement in psychology, and Matt finds out what happens to all those unreported clinical trials.
Matt, Chris, and Don finally take on one of their own studies and see how it holds up, the gang discusses what to do when your study has flaws, and Chris tells us what happens if you don’t get funding as a junior faculty member.
Matt, Chris, and Don tackle a study on the effectiveness of opioids vs non-opioids for chronic pain, the gang discusses new NIH rules on how a clinical trial is defined, and Matt reads us some academic love poems.
Matt, Chris, and Don are joined by two faculty from the BUSPH Biostats Department to discuss a massive meta-analysis on the effectiveness of antidepressants, then we talk about the pros and cons of meta-analysis, and Don gives us some driving advice.
Matt, Chris, and Don discuss a study on the HPV vaccine and its impact on prevalence of HPV, the gang discusses what the goal of peer review is, and Matt gets on twitter to find out the latest on significance.
